Anti-PC Responses of TdtL, TdtS, and Tdt−/−
. | . | . | . | Serum Abs . | |||
---|---|---|---|---|---|---|---|
Genotype . | Mice . | IgM . | PC . | TC68 . | TC139 . | AB1.2 . | GB4.10 . |
n | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | |
Tdt−/− | 20 | 477.8 (2.5) | 149.3 (2.0) | 159.3 (1.9) | 120.8 (2.0) | 121.8 (2.0) | 162.8 (2.1) |
TdtL I+/Tdt−/− | 5 | 475.3 (2.3) | 127.5 (1.6) | 140.4 (1.7) | 109.1 (1.5) | 119.7 (1.4) | 148.9 (1.7) |
Tdt+/+ | 13 | 414.7 (2.2) | 83.6 (1.6) | 92.9 (1.8) | 74.3 (1.7) | 79.7 (1.7) | 86.4 (1.7) |
TdtL I+/Tdt+/+ | 11 | 437.5 (2.1) | 79.9 (1.7) | 81.0 (1.8) | 60.6 (1.6) | 60.5 (1.7) | 77.0 (1.9) |
TdtS T+/Tdt+/+ | 5 | 416.8 (2.2) | 40.0 (1.3) | 38.4 (1.9) | 20.4 (1.2) | 20.0 (1.3) | 22.5 (1.4) |
TdtS V+/Tdt+/+ | 5 | 426 (1.3) | 178 (1.7) | 160 (1.8) | ND | 19 (1.1) | 15 (0.95) |
. | . | . | . | Serum Abs . | |||
---|---|---|---|---|---|---|---|
Genotype . | Mice . | IgM . | PC . | TC68 . | TC139 . | AB1.2 . | GB4.10 . |
n | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | μg/ml (log 10 SD) | |
Tdt−/− | 20 | 477.8 (2.5) | 149.3 (2.0) | 159.3 (1.9) | 120.8 (2.0) | 121.8 (2.0) | 162.8 (2.1) |
TdtL I+/Tdt−/− | 5 | 475.3 (2.3) | 127.5 (1.6) | 140.4 (1.7) | 109.1 (1.5) | 119.7 (1.4) | 148.9 (1.7) |
Tdt+/+ | 13 | 414.7 (2.2) | 83.6 (1.6) | 92.9 (1.8) | 74.3 (1.7) | 79.7 (1.7) | 86.4 (1.7) |
TdtL I+/Tdt+/+ | 11 | 437.5 (2.1) | 79.9 (1.7) | 81.0 (1.8) | 60.6 (1.6) | 60.5 (1.7) | 77.0 (1.9) |
TdtS T+/Tdt+/+ | 5 | 416.8 (2.2) | 40.0 (1.3) | 38.4 (1.9) | 20.4 (1.2) | 20.0 (1.3) | 22.5 (1.4) |
TdtS V+/Tdt+/+ | 5 | 426 (1.3) | 178 (1.7) | 160 (1.8) | ND | 19 (1.1) | 15 (0.95) |