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Table 1

Fg Checkerboard Analysis

Fn concentration (upper well)
Fg concentration(lower well)50 μg/ml10 μg/ml1 μg/mlMedium only
Medium 32 18 12 16 
1 μg/ml 25 18 15 29 
10 μg/ml 26 29 26 58 
50 μg/ml 24 65 101 100 
 
Fn concentration (upper well)
Fg concentration(lower well)50 μg/ml10 μg/ml1 μg/mlMedium only
Medium 32 18 12 16 
1 μg/ml 25 18 15 29 
10 μg/ml 26 29 26 58 
50 μg/ml 24 65 101 100 
 

Migration of αMβ2 WT 293 transfected cells was assessed as in the legend to Fig. 1 A to different concentrations of Fg placed either in the upper or lower transwells. Data are means of cells per HPF for duplicate wells from three or more experiments expressed as percentage of WT (migration to 50 μg/ml Fg, lower well).

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