The Distribution of P-lig and α4β7 Among Gated Memory T Cells in Secondary Lymphoid Tissues
Tissue . | Percentage of P-lig+α4β7− . | Percentage of P-lig−α4β7+ . | Percentage of P-lig−α4β7− . | Percentage of P-lig+α4β7+ . |
|---|---|---|---|---|
| PLNs | 37.1 ± 3.5 | 18.9 ± 1.6 | 42.7 ± 3.0 | 1.3 ± 0.7 |
| MLNs | 4.3 ± 0.7 | 62.3 ± 4.4 | 29.0 ± 5.8 | 4.5 ± 1.7 |
| PP | 1.2 ± 0.2 | 63.5 ± 5.5 | 32.6 ± 5.9 | 2.7 ± 0.5 |
| Spleen | 17.4 ± 2.0 | 29.2 ± 4.8 | 50.3 ± 5.5 | 3.1 ± 1.3 |
Tissue . | Percentage of P-lig+α4β7− . | Percentage of P-lig−α4β7+ . | Percentage of P-lig−α4β7− . | Percentage of P-lig+α4β7+ . |
|---|---|---|---|---|
| PLNs | 37.1 ± 3.5 | 18.9 ± 1.6 | 42.7 ± 3.0 | 1.3 ± 0.7 |
| MLNs | 4.3 ± 0.7 | 62.3 ± 4.4 | 29.0 ± 5.8 | 4.5 ± 1.7 |
| PP | 1.2 ± 0.2 | 63.5 ± 5.5 | 32.6 ± 5.9 | 2.7 ± 0.5 |
| Spleen | 17.4 ± 2.0 | 29.2 ± 4.8 | 50.3 ± 5.5 | 3.1 ± 1.3 |
Percentage of CD4+CD45RB− cells isolated from the PLNs, MLNs, PP or spleen with the indicated surface phenotype (defined by quadrant gate shown in Fig. 1). Data are mean and SD of values obtained from three age-matched (>1-y-old) BALB/c mice.
MLN, mesenteric LN; PLN, peripheral LN; PP, Peyer's patches.