Table I.

Increased CFU-S d12 in the Bone Marrow of the lnk−/− Mice


Genotype

CFU-S d12 (per 105 cells)
lnk+/+ 11.5 ± 2.4 
lnk−/−
 
20.8 ± 3.3a
 

Genotype

CFU-S d12 (per 105 cells)
lnk+/+ 11.5 ± 2.4 
lnk−/−
 
20.8 ± 3.3a
 
a

P < 0.01.

Bone marrow cells (105) were administered intravenously to lethally irradiated recipient mice. The spleens were removed and fixed 12 d after injection, and the number of colones was counted. The values are mean ± SD for quadruplicates.

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