Hematologic Parameters in wt and ΔdblGATA Mice With or Without an IL-5 Transgene
Sex . | dblGATA Genotype . | IL-5 Tg . | WBC . | Manual EO . |
|---|---|---|---|---|
| 103/μl | % | |||
| F | het | − | 5.76 | 1 |
| F | het | + | 43.34 | 3 |
| F | het | + | 24.83 | 10 |
| M | wt | + | 29.4 | 10 |
| M | wt | + | 75.69 | 9 |
| M | hem | − | 8.31 | 0 |
| M | hem | + | 50.35 | 0 |
| M | hem | + | 46.65 | 0 |
Sex . | dblGATA Genotype . | IL-5 Tg . | WBC . | Manual EO . |
|---|---|---|---|---|
| 103/μl | % | |||
| F | het | − | 5.76 | 1 |
| F | het | + | 43.34 | 3 |
| F | het | + | 24.83 | 10 |
| M | wt | + | 29.4 | 10 |
| M | wt | + | 75.69 | 9 |
| M | hem | − | 8.31 | 0 |
| M | hem | + | 50.35 | 0 |
| M | hem | + | 46.65 | 0 |
Automated measurement of blood from adult wt and ΔdblGATA mutant mouse littermates from a cross between heterozygous ΔdblGATA mutant female and a male heterozygous for an IL-5 transgene (see text for details). For an explanation of abbreviations, see Table I. The IL-5 transgene stimulates eosinophilia in heterozygous females and wt males but not in male mice hemizygous for the ΔdblGATA mutant allele. Manual EO, manual differential count of eosinophils by a blinded observer; WBC, leukocyte count.