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Table II.

Hematologic Parameters in wt and ΔdblGATA Mice With or Without an IL-5 Transgene


Sex

dblGATA Genotype

IL-5 Tg

WBC

Manual EO
   103/μl 
het − 5.76 
het 43.34 
het 24.83 10 
wt 29.4 10 
wt 75.69 
hem − 8.31 
hem 50.35 
M
 
hem
 
+
 
46.65
 
0
 

Sex

dblGATA Genotype

IL-5 Tg

WBC

Manual EO
   103/μl 
het − 5.76 
het 43.34 
het 24.83 10 
wt 29.4 10 
wt 75.69 
hem − 8.31 
hem 50.35 
M
 
hem
 
+
 
46.65
 
0
 

Automated measurement of blood from adult wt and ΔdblGATA mutant mouse littermates from a cross between heterozygous ΔdblGATA mutant female and a male heterozygous for an IL-5 transgene (see text for details). For an explanation of abbreviations, see Table I. The IL-5 transgene stimulates eosinophilia in heterozygous females and wt males but not in male mice hemizygous for the ΔdblGATA mutant allele. Manual EO, manual differential count of eosinophils by a blinded observer; WBC, leukocyte count.

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