α-GalCer Enhances Protective Immunity Induced by Malaria Immunogens
Immunogen . | No. of mice protected /no. challenged . | Percent protection (no parasitemia) . |
|---|---|---|
| γ-spza | 6/30 | 20 |
| γ-spz + α-GalCer | 28/30 | 93 |
| AdPγCSa | 2/30 | 7 |
| AdPγCS + α-GalCer | 24/30 | 80 |
| α-GalCer | 0/30 | 0 |
| None | 0/30 | 0 |
Immunogen . | No. of mice protected /no. challenged . | Percent protection (no parasitemia) . |
|---|---|---|
| γ-spza | 6/30 | 20 |
| γ-spz + α-GalCer | 28/30 | 93 |
| AdPγCSa | 2/30 | 7 |
| AdPγCS + α-GalCer | 24/30 | 80 |
| α-GalCer | 0/30 | 0 |
| None | 0/30 | 0 |
BALB/c mice were immunized either intravenously with 104 γ-spz or subcutaneously with 107 PFU of AdPγCS.