Clonogenic Progenitor Assay Reveals a Differentiation Block in Myeloid Progenitors
BMa . | No. of colonies per 105 cellsb . | . | Mean distribution of mature colonies (%) . | . | . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Immature . | Mature . | CFU-Mix . | CFU-GM . | CFU-G . | CFU-M . | BFU-E . | |||||
AEpos | 196 ± 60 | 17 ± 7 | 6.1 | 19.3 | 7.2 | 42.0 | 24.2 | |||||
GFPpos | 0 | 49 ± 22 | 2.3 | 14.9 | 20.15 | 29.4 | 33.8 | |||||
Unsortedc | 0 | 50 ± 28 | 8.2 | 15.2 | 17.7 | 29.4 | 31.2 |
BMa . | No. of colonies per 105 cellsb . | . | Mean distribution of mature colonies (%) . | . | . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
. | Immature . | Mature . | CFU-Mix . | CFU-GM . | CFU-G . | CFU-M . | BFU-E . | |||||
AEpos | 196 ± 60 | 17 ± 7 | 6.1 | 19.3 | 7.2 | 42.0 | 24.2 | |||||
GFPpos | 0 | 49 ± 22 | 2.3 | 14.9 | 20.15 | 29.4 | 33.8 | |||||
Unsortedc | 0 | 50 ± 28 | 8.2 | 15.2 | 17.7 | 29.4 | 31.2 |