Effect of Anti-TcOYE Polyclonal Antibody Treatment of T. cruzi Lysates on Drug Reduction
. | . | Percent residual reductase activity toward: . | . | . | ||
|---|---|---|---|---|---|---|
| Sample . | Menadione . | β-lapachone . | Nifurtimox . | 4-nitroquinoline-N-oxide . | ||
| Lysates from treatment with anti-TcOYE polyclonal antibody | n.d. | 10 (±2) | n.d. | n.d. | ||
| Lysates from treatment with anti-TbPGFS polyclonal antibody | 98 (±8) | 103 (±3) | 100 (±5) | 100 (±10) | ||
| Lysates from treatment with bovine IgG | 100 (±4) | 100 (±6) | 100 (±10) | 100 (±6) | ||
. | . | Percent residual reductase activity toward: . | . | . | ||
|---|---|---|---|---|---|---|
| Sample . | Menadione . | β-lapachone . | Nifurtimox . | 4-nitroquinoline-N-oxide . | ||
| Lysates from treatment with anti-TcOYE polyclonal antibody | n.d. | 10 (±2) | n.d. | n.d. | ||
| Lysates from treatment with anti-TbPGFS polyclonal antibody | 98 (±8) | 103 (±3) | 100 (±5) | 100 (±10) | ||
| Lysates from treatment with bovine IgG | 100 (±4) | 100 (±6) | 100 (±10) | 100 (±6) | ||
n.d., not detected. Values shown are the mean along with SE from three independent experiments.