Rockefeller University Press

Table I.

Flt3L Expands Lymphoid and Myeloid Progenitors In Vivo

	5 Days							10 Days
	Control			Flt3L s.c.			Control			Flt3L s.c.	5 Days	10 Days
	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³
HSC^{^a}	0.03	17.5	0.14	96.6	0.03	16.2	0.09	65.3	5.5	4
CLP^{^a}	0.03	12.5	0.05	34.5	0.02	10.8	0.04	29	2.8	2.7
CMP^{^a}	0.22	110	0.71	490	0.22	119	0.48	348	4.4	2.9
GMP^{^a}	0.5	250	3.5	2,415	0.4	216	1.9	1,378	9.7	6.4
MEP^{^a}	0.12	60	0.1	69	0.08	43.2	0.065	47.1	1.2	1.1
pB(A)^{^a}	0.4	200	0.5	345	0.45	243	1.8	1,305	1.7	5.4
pB(BC)^{^a}	1.5	750	1.3	897	1.5	810	0.4	290	1.2	0.36
pT1^{^b}	0.02	30	0.08	104	0.02	30	0.05	60	3.5	2
pT2^{^b}	0.07	105	0.15	195	0.06	90	0.05	60	1.9	0.7

	5 Days							10 Days
	Control			Flt3L s.c.			Control			Flt3L s.c.	5 Days	10 Days
	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³
HSC^{^a}	0.03	17.5	0.14	96.6	0.03	16.2	0.09	65.3	5.5	4
CLP^{^a}	0.03	12.5	0.05	34.5	0.02	10.8	0.04	29	2.8	2.7
CMP^{^a}	0.22	110	0.71	490	0.22	119	0.48	348	4.4	2.9
GMP^{^a}	0.5	250	3.5	2,415	0.4	216	1.9	1,378	9.7	6.4
MEP^{^a}	0.12	60	0.1	69	0.08	43.2	0.065	47.1	1.2	1.1
pB(A)^{^a}	0.4	200	0.5	345	0.45	243	1.8	1,305	1.7	5.4
pB(BC)^{^a}	1.5	750	1.3	897	1.5	810	0.4	290	1.2	0.36
pT1^{^b}	0.02	30	0.08	104	0.02	30	0.05	60	3.5	2
pT2^{^b}	0.07	105	0.15	195	0.06	90	0.05	60	1.9	0.7

legs or

thymus after 5 and 10 d of Flt3L or PBS injection, respectively. Results represent means of three to four animals per group and are representative of three independent experiments.

Relative percentages and total cell count of hematopoietic progenitor populations in bone marrow of two hind

View Large

This Feature Is Available To Subscribers Only