Rockefeller University Press

Table II.

Expansion of Spleen Cells after Flt3L Injections

	5 Days							10 Days
	Control			Flt3L s.c.			Control			Flt3L s.c.	5 Days	10 Days
	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³
B cells	61	67,100	54	72,900	55	67,000	26	68,900	1.1	1.0
T cells	35	38,500	36	48,600	36	44,000	21	55,600	1.3	1.3
Neutrophils	0.9	990	1.6	2,160	0.5	610	5.9	15,630	2.2	25.5
Monocytes	3.3	3,600	6.1	8,235	2	2,400	9.4	11,470	2.3	4.8
DCs	0.6	660	2.7	3,645	0.6	730	12.6	15,370	5.5	21
IPCs	0.04	44	0.07	95	0.05	61	1.4	1,708	2.2	28
CLP-DCs^{^a}					0.1	106	0.35	424		3.9
CMP-DCs^{^a}					0.17	176	0.47	572		3.2

	5 Days							10 Days
	Control			Flt3L s.c.			Control			Flt3L s.c.	5 Days	10 Days
	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³	percent	total no. ×10³
B cells	61	67,100	54	72,900	55	67,000	26	68,900	1.1	1.0
T cells	35	38,500	36	48,600	36	44,000	21	55,600	1.3	1.3
Neutrophils	0.9	990	1.6	2,160	0.5	610	5.9	15,630	2.2	25.5
Monocytes	3.3	3,600	6.1	8,235	2	2,400	9.4	11,470	2.3	4.8
DCs	0.6	660	2.7	3,645	0.6	730	12.6	15,370	5.5	21
IPCs	0.04	44	0.07	95	0.05	61	1.4	1,708	2.2	28
CLP-DCs^{^a}					0.1	106	0.35	424		3.9
CMP-DCs^{^a}					0.17	176	0.47	572		3.2

Percentages and total numbers of CLP- and CMP-derived DCs in spleens of transplanted animals after 10 d of Flt3L or PBS treatment, respectively. Results represent means of three experiments each involving two to four animals in the Flt3L injection and two mice in the control group.

Changes in relative percentages and total cell number of mature hematopoietic populations in the spleen after 5 and 10 d of injections with Flt3L or PBS (control group), respectively. Results represent means of three to four animals per group and are representative of three independent experiments.

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