Features of Naive, Effector, and Central and Effector Memory CD8+ T Cells
. | Degranulation program . | Effector molecules stored in granules . | Cytotoxicity (4–6 h) . | De novo synthesis of effector molecules (5 h) . | IFNγ synthesis(2–4 h) . |
|---|---|---|---|---|---|
| Naive | − | − | − | − | − |
| Effector | +++ | +++ | +++ | ++ | +++ |
| Effector memory | +++ | + | + | + | +++ |
| Central memory | +++ | − | − | + | +++ |
. | Degranulation program . | Effector molecules stored in granules . | Cytotoxicity (4–6 h) . | De novo synthesis of effector molecules (5 h) . | IFNγ synthesis(2–4 h) . |
|---|---|---|---|---|---|
| Naive | − | − | − | − | − |
| Effector | +++ | +++ | +++ | ++ | +++ |
| Effector memory | +++ | + | + | + | +++ |
| Central memory | +++ | − | − | + | +++ |