Mean ± SEM of Diameter, Interfacial Shear Rate γi and Newtonian Wall Shear Rate of γw of Venules in TNF-α–treated WT or E-Selectin−/− Mice with (+) or without (−) PTx Treatment
. | PTx . | 9A9 . | dia . | γi . | Newtonian γw . |
|---|---|---|---|---|---|
| μm | s−1 | s−1 | |||
| C57B1/6 | |||||
| WT | − | − | 36.2 ± 3 | 1,433 ± 218 | 292 ± 44 |
| + | − | 35.3 ± 3 | 1,052 ± 122 | 215 ± 25 | |
| + | + | 30.5 ± 4 | 1,070 ± 160 | 218 ± 33 | |
| E-selectin−/− | − | − | 33.8 ± 2 | 1,265 ± 179 | 258 ± 37 |
| + | − | 29.1 ± 2 | 1,419 ± 216 | 290 ± 44 | |
| BALB/c | |||||
| WT | − | − | 33.5 ± 2 | 1,362 ± 144 | 278 ± 29 |
| CXCR2−/− | − | − | 31.5 ± 2 | 1,278 ± 48 | 261 ± 20 |
| − | + | 34.8 ± 2 | 1,106 ± 112 | 226 ± 23 |
. | PTx . | 9A9 . | dia . | γi . | Newtonian γw . |
|---|---|---|---|---|---|
| μm | s−1 | s−1 | |||
| C57B1/6 | |||||
| WT | − | − | 36.2 ± 3 | 1,433 ± 218 | 292 ± 44 |
| + | − | 35.3 ± 3 | 1,052 ± 122 | 215 ± 25 | |
| + | + | 30.5 ± 4 | 1,070 ± 160 | 218 ± 33 | |
| E-selectin−/− | − | − | 33.8 ± 2 | 1,265 ± 179 | 258 ± 37 |
| + | − | 29.1 ± 2 | 1,419 ± 216 | 290 ± 44 | |
| BALB/c | |||||
| WT | − | − | 33.5 ± 2 | 1,362 ± 144 | 278 ± 29 |
| CXCR2−/− | − | − | 31.5 ± 2 | 1,278 ± 48 | 261 ± 20 |
| − | + | 34.8 ± 2 | 1,106 ± 112 | 226 ± 23 |