Table I.

Clinical parameters of MOG35–55-induced EAE


Genotype

Incidence

Mean day
 of onseta

Mean maximal
 clinical scorea

Number of mice
 with
 maximal score ≥2.5
PAFR-WT 28/29 13.6 ± 0.4 2.9 ± 0.2 25 
PAFR-KO
 
20/29b
 
13.1 ± 0.3
 
2.6 ± 0.2c
 
14b
 

Genotype

Incidence

Mean day
 of onseta

Mean maximal
 clinical scorea

Number of mice
 with
 maximal score ≥2.5
PAFR-WT 28/29 13.6 ± 0.4 2.9 ± 0.2 25 
PAFR-KO
 
20/29b
 
13.1 ± 0.3
 
2.6 ± 0.2c
 
14b
 
a

Mice with score 0 were excluded from the data. Data represent means ± SEM.

b

P < 0.05 by Fisher's exact test.

c

P < 0.05 by Mann-Whitney U test, significantly different from the PAFR-WT group.

Composite data from three independent experiments are shown.

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