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Table I.

Phenotype of patients

Characteristic
P1
P2a
P3a
P4
P5
Age-matched controls
Age at diagnosis (yr) — 
Serum Ig levels (g/l)      — 
    IgM 16 4.1 2.6 2.8 0.9 0.5–1.2 
    IgG 0.6 3.6 5.7 0.7 1.4 6.8–12.5 
    IgA 0.3 <0.03 <0.03 <0.03 <0.03 0.6–1.6 
T lymphocyte counts/μl 2,400 1,420 1,238 1,612 1,300 1,200–2,600 
B lymphocyte counts/μl 452 120 170 462 440 110–570 
IgD+/CD19+ (%)b 99.9 99.2 ND 99.8 ND 83–93 
CD27+/CD19+ (%)b 1.5 3.3 3.1 4.7 3.1 13–58 
Characteristic
P1
P2a
P3a
P4
P5
Age-matched controls
Age at diagnosis (yr) — 
Serum Ig levels (g/l)      — 
    IgM 16 4.1 2.6 2.8 0.9 0.5–1.2 
    IgG 0.6 3.6 5.7 0.7 1.4 6.8–12.5 
    IgA 0.3 <0.03 <0.03 <0.03 <0.03 0.6–1.6 
T lymphocyte counts/μl 2,400 1,420 1,238 1,612 1,300 1,200–2,600 
B lymphocyte counts/μl 452 120 170 462 440 110–570 
IgD+/CD19+ (%)b 99.9 99.2 ND 99.8 ND 83–93 
CD27+/CD19+ (%)b 1.5 3.3 3.1 4.7 3.1 13–58 
a

P2 and P3 are siblings.

b

Gated on CD19+ B cells.

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