Skip to Main Content
Table 1.
Percentages of lung tryptase activity due to α/β-tryptase after purification of tryptase by B2-agarose immunoaffinity chromatography (P0)
GenotypeTryptase activity in P2 (%)aTryptase activity based on stability to B12 inhibition (%)bn
αβ:ββ 15 ± 2 15 ± 1 
αβ:αβ 30 ± 7 46 ± 5 
ββ:ααβc 27 27 
ββ:αααβc 37 43 
GenotypeTryptase activity in P2 (%)aTryptase activity based on stability to B12 inhibition (%)bn
αβ:ββ 15 ± 2 15 ± 1 
αβ:αβ 30 ± 7 46 ± 5 
ββ:ααβc 27 27 
ββ:αααβc 37 43 

Values are presented as mean ± SD. Data represent two replicate experiments for each of the three different individuals with an αβ:ββ or αβ:αβ tryptase genotype in column 2, triplicate values for each of the three different subjects with an αβ:ββ or αβ:αβ tryptase genotype in column 3, two replicates from the one subject with a ββ:ααβ or a ββ:αααβ tryptase genotype in column 2, and three replicates from the one subject with a ββ:ααβ or a ββ:αααβ tryptase genotype in column 3.

a

100 × P2/(P1 + P2).

b

Percentage activity after 20 min compared to β-tryptase (P0, ββ:ββ genotype) and α/β-tryptase (P2, ββ:αααβ genotype).

c

Hereditary α-tryptasemia genotype.

Close Modal

or Create an Account

Close Modal
Close Modal