Rockefeller University Press

Table 1.

Mouse RPE/choroid cell types identified by scRNAseq

Cluster number	Cell type	Cell number		Percentage of total		Average UMIs/cell		Average genes/cell		Average UMIs/gene
Cluster number	Cell type	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice
1	RPE	402	445	10.1	11.9	4,860	7,514	1,468	1,911	3.02	3.51
2	ECs	405	366	10.1	9.8	4,550	5,151	1,920	2,090	2.18	2.32
3	ECs	550	435	13.8	11.7	4,847	5,570	1,943	2,139	2.28	2.42
4	ECs	74	63	1.9	1.7	4,749	5,196	1,894	2,025	2.26	2.37
5	Stromal cells	776	797	19.4	21.4	3,255	3,723	1,524	1,645	2.09	2.21
6	Stromal cells	610	552	15.3	14.8	3,171	3,796	1,491	1,681	2.07	2.21
7	Stromal cells	223	229	5.6	6.1	3,695	4,518	1,684	1,894	2.14	2.32
8	Stromal cells	158	166	4.0	4.5	2,995	3,944	1,391	1,661	2.13	2.33
9	Smooth muscle cells	476	400	11.9	10.7	3,863	4,769	1,583	1,814	2.38	2.58
10	Melanocytes	28	20	0.7	0.5	3,913	5,008	1,621	1,847	2.32	2.59
11	Hematopoietic cells	140	116	3.5	3.1	4,573	4,960	1,528	1,496	2.83	3.19
12	Schwann cells	108	106	2.7	2.8	2,525	2,835	1,306	1,418	1.90	1.96
13	Schwann cells	46	32	1.2	0.9	2,606	3,532	1,227	1,495	2.08	2.31
	Total	3,996	3,727

Cluster number	Cell type	Cell number		Percentage of total		Average UMIs/cell		Average genes/cell		Average UMIs/gene
Cluster number	Cell type	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice	C57BL/6J mice	B6129PF1/J mice
1	RPE	402	445	10.1	11.9	4,860	7,514	1,468	1,911	3.02	3.51
2	ECs	405	366	10.1	9.8	4,550	5,151	1,920	2,090	2.18	2.32
3	ECs	550	435	13.8	11.7	4,847	5,570	1,943	2,139	2.28	2.42
4	ECs	74	63	1.9	1.7	4,749	5,196	1,894	2,025	2.26	2.37
5	Stromal cells	776	797	19.4	21.4	3,255	3,723	1,524	1,645	2.09	2.21
6	Stromal cells	610	552	15.3	14.8	3,171	3,796	1,491	1,681	2.07	2.21
7	Stromal cells	223	229	5.6	6.1	3,695	4,518	1,684	1,894	2.14	2.32
8	Stromal cells	158	166	4.0	4.5	2,995	3,944	1,391	1,661	2.13	2.33
9	Smooth muscle cells	476	400	11.9	10.7	3,863	4,769	1,583	1,814	2.38	2.58
10	Melanocytes	28	20	0.7	0.5	3,913	5,008	1,621	1,847	2.32	2.59
11	Hematopoietic cells	140	116	3.5	3.1	4,573	4,960	1,528	1,496	2.83	3.19
12	Schwann cells	108	106	2.7	2.8	2,525	2,835	1,306	1,418	1.90	1.96
13	Schwann cells	46	32	1.2	0.9	2,606	3,532	1,227	1,495	2.08	2.31
	Total	3,996	3,727

Data are from C57BL/6J and B6129PF1/J mice (pooled cells from one male and one female for each strain).