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Table II.

V_H3.15 repertoire analysis of the splenic B cell subsets of an 8-mo-old child

Donor	B cell subset	Transcripts	Number of peaks  analyzed^{^a}	Total number of  sequences	Number of different  VDJ junctions	Clonal  diversity^{^b}	P value^{^c}
						%
D3	IgD⁺CD27⁺	V_H3.15 μ	3	58	56	97
	Naives	V_H3.15 μ	3	71	64	90
	IgD⁻CD27⁺  (switched + GC)	V_H3.15 γ	3	73	35	48	3 × 10⁻⁹
	CD38⁺CD24⁻  (GC)	V_H3.15 μ	6	133	71	53	4 × 10⁻⁹
		V_H3.15 γ	5	98	51	52	10⁻⁸

Donor	B cell subset	Transcripts	Number of peaks  analyzed^{^a}	Total number of  sequences	Number of different  VDJ junctions	Clonal  diversity^{^b}	P value^{^c}
						%
D3	IgD⁺CD27⁺	V_H3.15 μ	3	58	56	97
	Naives	V_H3.15 μ	3	71	64	90
	IgD⁻CD27⁺  (switched + GC)	V_H3.15 γ	3	73	35	48	3 × 10⁻⁹
	CD38⁺CD24⁻  (GC)	V_H3.15 μ	6	133	71	53	4 × 10⁻⁹
		V_H3.15 γ	5	98	51	52	10⁻⁸

The peaks that were analyzed are identified by an asterisk in Fig. 2.

Number of different VDJ among all sequences.

Statistical significance (see Materials and methods) of differences in clonal diversity between IgD⁺CD27⁺ and IgD⁻CD27⁺ or GC cells from the same donor.

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