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Table II.

Transcript levels of SPARC-related factor messenger RNAs (mRNAs)

	Sham				3-d MI
	WT M (n = 7)	WT F (n = 7)	KO M (n = 7)	KO F (n = 7)	WT M (n = 6)	WT F (n = 8)	KO M (n = 5)	KO F (n = 10)
SMOC1	11 ± 1.1	12 ± 1.5	13 ± 4.3	11 ± 1.4	35 ± 6.8^a	34 ± 5.3^a	26 ± 6.4^a	27 ± 5.4^a
SMOC2	5.0 ± 0.9	10 ± 0.5^b	7.3 ± 0.6	9.3 ± 0.3^b	3.4 ± 0.5	3.0 ± 0.5^a	4.2 ± 0.7^a	4.8 ± 0.6^a^c
Hevin	1.0 ± 0.1	1.2 ± 0.1	1.0 ± 0.1	0.8 ± 0.1^c	0.8 ± 0.1	0.7 ± 0.1^a	0.6 ± 0.1	0.7 ± 0.1
SPARC	3.4 ± 1.5	1.8 ± 0.1	ND	ND	14 ± 1.6^a	16 ± 1.8^a	ND	ND

	Sham				3-d MI
	WT M (n = 7)	WT F (n = 7)	KO M (n = 7)	KO F (n = 7)	WT M (n = 6)	WT F (n = 8)	KO M (n = 5)	KO F (n = 10)
SMOC1	11 ± 1.1	12 ± 1.5	13 ± 4.3	11 ± 1.4	35 ± 6.8^a	34 ± 5.3^a	26 ± 6.4^a	27 ± 5.4^a
SMOC2	5.0 ± 0.9	10 ± 0.5^b	7.3 ± 0.6	9.3 ± 0.3^b	3.4 ± 0.5	3.0 ± 0.5^a	4.2 ± 0.7^a	4.8 ± 0.6^a^c
Hevin	1.0 ± 0.1	1.2 ± 0.1	1.0 ± 0.1	0.8 ± 0.1^c	0.8 ± 0.1	0.7 ± 0.1^a	0.6 ± 0.1	0.7 ± 0.1
SPARC	3.4 ± 1.5	1.8 ± 0.1	ND	ND	14 ± 1.6^a	16 ± 1.8^a	ND	ND

M, male; F, female; ND, not detectable. Numbers are in arbitrary units.

P < 0.05 in MI group versus respective sham.

P < 0.05 between males and females of the same genotype.

P < 0.05 between WT and SPARC-null mice of the same gender.