Rockefeller University Press

Table I.

Number and cellular origins of MPs (×10⁶/liter⁻¹ plasma) in healthy and cancer mice

MP origins	Controls (n = 8)	Pancreatic cancer (n = 8)	Lung cancer (n = 7)	p-value^a	p-value^b
	×10⁶/liter⁻¹ plasma	×10⁶/liter⁻¹ plasma	×10⁶/liter⁻¹ plasma
Total (annexin V⁺)
Median	8,951	9,383	10,018	0.024	0.047
Range	5,994–14,714	5,536–14,794	5,048–16,442
Platelet (CD41⁺)
Median	2,294	3096	3,024	0.035	0.014
Range	1,724–3,216	1,636–5,476	770–8,784
Erythrocyte (TER 119⁺)
Median	1,410	694	828	0.149	0.242
Range	250–4,672	288–2,712	478–2,480
Leukocyte (CD45⁺)
Median	346	251	722	0.209	0.424
Range	74–1,032	130–888	68–2,206
Endothelial cell (CD31⁺CD41⁻)
Median	135	275	164	0.001	0.014
Range	108–330	150–336	92–296
MUC-1⁺
Median	117	1089	1,492	0.003	0.003
Range	0–7,424	0–15,468	98–4,786
CA19.9⁺
Median	0	264	127	0.001	0.003
Range	0	0–6,852	0–2,428 (n = 6)
Annexin V⁺ PSGL-1⁺
Median	146	293	234	0.004	0.006
Range	76–376	74–522	134–550

MP origins	Controls (n = 8)	Pancreatic cancer (n = 8)	Lung cancer (n = 7)	p-value^a	p-value^b
	×10⁶/liter⁻¹ plasma	×10⁶/liter⁻¹ plasma	×10⁶/liter⁻¹ plasma
Total (annexin V⁺)
Median	8,951	9,383	10,018	0.024	0.047
Range	5,994–14,714	5,536–14,794	5,048–16,442
Platelet (CD41⁺)
Median	2,294	3096	3,024	0.035	0.014
Range	1,724–3,216	1,636–5,476	770–8,784
Erythrocyte (TER 119⁺)
Median	1,410	694	828	0.149	0.242
Range	250–4,672	288–2,712	478–2,480
Leukocyte (CD45⁺)
Median	346	251	722	0.209	0.424
Range	74–1,032	130–888	68–2,206
Endothelial cell (CD31⁺CD41⁻)
Median	135	275	164	0.001	0.014
Range	108–330	150–336	92–296
MUC-1⁺
Median	117	1089	1,492	0.003	0.003
Range	0–7,424	0–15,468	98–4,786
CA19.9⁺
Median	0	264	127	0.001	0.003
Range	0	0–6,852	0–2,428 (n = 6)
Annexin V⁺ PSGL-1⁺
Median	146	293	234	0.004	0.006
Range	76–376	74–522	134–550

Differences between mice developing a pancreatic cancer and healthy mice.

Differences between mice developing a lung cancer and healthy mice.