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Table II.

Most significantly enriched GO categories in gene set regulated >2 fold in PbeIK2 (-) compared to wild-type salivary gland sporozoites

GO accession no.	GO term	P-value	Count in selection	Count in selection	Count in total	Count in total
				%		%
GO:0010467	gene expression	0.0252	94	94.95	567	18.67
GO:0022626	cytosolic ribosome	0.0252	38	38.38	149	4.91
GO:0033279	ribosomal subunit	0.0373	42	42.42	178	5.86
GO:0022625	cytosolic large ribosomal subunit	0.0373	34	34.34	131	4.31
GO:0044445	cytosolic part	0.0393	40	40.40	177	5.83
GO:0015934	large ribosomal subunit	0.0393	37	37.37	151	4.97
GO:0022613	ribonucleoprotein complex biogenesis and assembly	0.0393	51	51.52	249	8.20
GO:0005840	ribosome	0.0433	48	48.48	224	7.38
GO:0005829	cytosol	0.0478	40	40.40	180	5.93
GO:0030529	ribonucleoprotein complex	0.0697	54	54.55	270	8.89
GO:0022618	ribonucleoprotein complex assembly	0.0743	45	45.45	217	7.15
GO:0006412	translation	0.0757	68	68.69	372	12.25
GO:0006413	translational initiation	0.0785	45	45.45	212	6.98

GO accession no.	GO term	P-value	Count in selection	Count in selection	Count in total	Count in total
				%		%
GO:0010467	gene expression	0.0252	94	94.95	567	18.67
GO:0022626	cytosolic ribosome	0.0252	38	38.38	149	4.91
GO:0033279	ribosomal subunit	0.0373	42	42.42	178	5.86
GO:0022625	cytosolic large ribosomal subunit	0.0373	34	34.34	131	4.31
GO:0044445	cytosolic part	0.0393	40	40.40	177	5.83
GO:0015934	large ribosomal subunit	0.0393	37	37.37	151	4.97
GO:0022613	ribonucleoprotein complex biogenesis and assembly	0.0393	51	51.52	249	8.20
GO:0005840	ribosome	0.0433	48	48.48	224	7.38
GO:0005829	cytosol	0.0478	40	40.40	180	5.93
GO:0030529	ribonucleoprotein complex	0.0697	54	54.55	270	8.89
GO:0022618	ribonucleoprotein complex assembly	0.0743	45	45.45	217	7.15
GO:0006412	translation	0.0757	68	68.69	372	12.25
GO:0006413	translational initiation	0.0785	45	45.45	212	6.98

P-values were corrected for GO category dependencies. Microarray arrays data are the means of two wild-type salivary gland sporozoites and two PbeIK2 (-) clones.

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