Expression of major surface glycoproteins on FlnA-null platelets
| Platelet glycoprotein | FlnA+/y | FlnAloxP/y | P-value |
| GPIbα (CD42b) | 62.6 ± 3.2 | 34.2 ± 3.7 | <0.005 |
| GPIbβ (CD42c) | 330.7 ± 43.2 | 251.1 ± 5.9 | <0.05 |
| GPIX (CD42a) | 37.0 ± 6.3 | 27.8 ± 1.9 | NS |
| GPV (CD42d) | 67.3 ± 10.7 | 46.8 ± 4.1 | NS |
| GPIIIa (CD61, integrin β3) | 45.9 ± 17.1 | 152.4 ± 16.5 | <0.005 |
| GPVI | 12.8 ± 2.8 | 17.9 ± 1.4 | <0.05 |
| Platelet glycoprotein | FlnA+/y | FlnAloxP/y | P-value |
| GPIbα (CD42b) | 62.6 ± 3.2 | 34.2 ± 3.7 | <0.005 |
| GPIbβ (CD42c) | 330.7 ± 43.2 | 251.1 ± 5.9 | <0.05 |
| GPIX (CD42a) | 37.0 ± 6.3 | 27.8 ± 1.9 | NS |
| GPV (CD42d) | 67.3 ± 10.7 | 46.8 ± 4.1 | NS |
| GPIIIa (CD61, integrin β3) | 45.9 ± 17.1 | 152.4 ± 16.5 | <0.005 |
| GPVI | 12.8 ± 2.8 | 17.9 ± 1.4 | <0.05 |
The binding of fluorescently labeled antibodies directed against the platelet glycoproteins indicated above was measured by flow cytometry. Data are expressed as mean fluorescence intensity bound to the surface of FlnA+/y GATA1-Cre and FlnAloxP/y GATA1-Cre platelets and represent mean ± SD (n = 4-5 for each independent group). NS indicates not significant.