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TABLE I

Comparison of the Kinetic Parameters for Fast and Slow Inactivation

	Fast inactivation			Slow inactivation
			Entry					Exit
	τ_recovery	n	τ_entry	S_∞ (−10 mV)	n	τ_recovery	n
	ms		ms			ms
Wild-type	2.2 ± 0.18	3	1,000 ± 160	0.06 ± 0.008	3	640 ± 40	4
Y401C	1.6 ± 0.13	4	1,000 ± 170	0.14 ± 0.035	5	710 ± 150	5
E403C	2.9 ± 0.75	6	2,100 ± 500	0.13 ± 0.021	5	890 ± 280	4
E758C	1.8 ± 0.19	4	2,600 ± 380^{^a}	0.19 ± 0.030^{^a}	7	450 ± 58^{^a}	4
M1240C	2.3 ± 0.26	5	2,400 ± 520	0.11 ± 0.025	4	620 ± 130	5
G1530C	2.5 ± 0.57	6	1,600 ± 280	0.07 ± 0.008	6	810 ± 53	4
D1532C	2.2 ± 0.62	3	1,200 ± 130	0.11 ± 0.032	3	470 ± 190	3

	Fast inactivation			Slow inactivation
			Entry					Exit
	τ_recovery	n	τ_entry	S_∞ (−10 mV)	n	τ_recovery	n
	ms		ms			ms
Wild-type	2.2 ± 0.18	3	1,000 ± 160	0.06 ± 0.008	3	640 ± 40	4
Y401C	1.6 ± 0.13	4	1,000 ± 170	0.14 ± 0.035	5	710 ± 150	5
E403C	2.9 ± 0.75	6	2,100 ± 500	0.13 ± 0.021	5	890 ± 280	4
E758C	1.8 ± 0.19	4	2,600 ± 380^{^a}	0.19 ± 0.030^{^a}	7	450 ± 58^{^a}	4
M1240C	2.3 ± 0.26	5	2,400 ± 520	0.11 ± 0.025	4	620 ± 130	5
G1530C	2.5 ± 0.57	6	1,600 ± 280	0.07 ± 0.008	6	810 ± 53	4
D1532C	2.2 ± 0.62	3	1,200 ± 130	0.11 ± 0.032	3	470 ± 190	3

^a

P < 0.04.