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Table II.

The tilt in the TM helices is shown for each of the open-state models as well as the magnitude of structural change required to move from the closed state to each open state

Model Tilt TM1 Tilt TM2 RMSD in subunit RMSD in pentamer 
   Å Å 
Closed 37.2 34.4   
0 dyn/cm 52.5 39.0 8.1 11.5 
5 dyn/cm 56.3 42.4 9.9 12.0 
60 dyn/cm 59.8 47.0 8.9 12.7 
Meyer (32) 51.2 54.5 12.6 17.7 
Sukharev (27) 71.5 56.3 9.5 33.2 
Model Tilt TM1 Tilt TM2 RMSD in subunit RMSD in pentamer 
   Å Å 
Closed 37.2 34.4   
0 dyn/cm 52.5 39.0 8.1 11.5 
5 dyn/cm 56.3 42.4 9.9 12.0 
60 dyn/cm 59.8 47.0 8.9 12.7 
Meyer (32) 51.2 54.5 12.6 17.7 
Sukharev (27) 71.5 56.3 9.5 33.2 

The structural change is determined by aligning either a single subunit to a subunit in the closed structure, or the whole pentamer to the closed pentameric structure, and presented as a root mean-square deviation (RMSD).

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