Skip to Main Content
Table I
PeptideKd*Internalization indexTurn propensity§
  mM     
FDNPVY  0.14  1.0  1.0 
FDNPVF  0.33  0.95  0.75 
FDNPVL  0.63  0.30  ND 
FDNPVS  1.4  0.20  
FDNPVA  3.1  0.20  
PeptideKd*Internalization indexTurn propensity§
  mM     
FDNPVY  0.14  1.0  1.0 
FDNPVF  0.33  0.95  0.75 
FDNPVL  0.63  0.30  ND 
FDNPVS  1.4  0.20  
FDNPVA  3.1  0.20  
*

 The relative Kd calculated from Phe(3,5) aromatic proton peak intensities as described in the experimental procedures.  

 Normalized to the native receptor (14).  

§

 Using NOE magnitudes as an indicator for turn propensity, scaled to that for the NPVY peptide (2). ND, not determined.  

Close Modal

or Create an Account

Close Modal
Close Modal