Table I
PeptideKd*Internalization indexTurn propensity§
mM
FDNPVY  0.14  1.0  1.0
FDNPVF  0.33  0.95  0.75
FDNPVL  0.63  0.30  ND
FDNPVS  1.4  0.20
FDNPVA  3.1  0.20
PeptideKd*Internalization indexTurn propensity§
mM
FDNPVY  0.14  1.0  1.0
FDNPVF  0.33  0.95  0.75
FDNPVL  0.63  0.30  ND
FDNPVS  1.4  0.20
FDNPVA  3.1  0.20
*

The relative Kd calculated from Phe(3,5) aromatic proton peak intensities as described in the experimental procedures.

Normalized to the native receptor (14).

§

Using NOE magnitudes as an indicator for turn propensity, scaled to that for the NPVY peptide (2). ND, not determined.

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