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Table II

Quantitation of Phagocytic Cup and Phagosome Formation in Wild-Type and gβ Cells Incubated with Yeast Particles

Strain(I) Adhesion events(II) Cup formationSuccess rate (II/I)(III) EngulfmentSuccess rate (III/I)
      (%)    (%) 
WT  115   90  78  56  48 
  252   152*  60  22   9 
Strain(I) Adhesion events(II) Cup formationSuccess rate (II/I)(III) EngulfmentSuccess rate (III/I)
      (%)    (%) 
WT  115   90  78  56  48 
  252   152*  60  22   9 

Adhesion events, cells and particles in close contact; phagocytic cup formation, half cup formed around a particle; engulfment, particle surrounded by the plasma membrane. The number of observed events is shown and the success rate calculated as percentage of successful phagocytic cup formation (II/I) or engulfment (III/I) in total adhesion events. Experimental conditions are as in Fig. 5. Values are from two experiments for WT and four for LW6.  

*

,  P = 0.0012;  

P < 0.0001 relative to WT (Chi-test).  

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