Table I

Effect of PKC βII Transgene Expression on Morphometric Parameters in the Colon

ControlTransgenicP value
Colon length (cm)    8.5 ± 0.2    8.6 ± 0.1  NS 
Crypt height (μm)  102.6 ± 3.9  108.3 ± 2.3  NS 
Crypt height (No. cells)   20.1 ± 0.4   22.3 ± 0.2  0.0002 
Cell size (crypt height [μm]/    5.1 ± 0.1    4.9 ± 0.1  NS 
 crypt height [No. cells])       
Crypt circumference (No. cells)   16.3 ± 0.3   16.8 ± 0.2  NS 
Total No. cells per crypt  327.7 ± 7.2  372.8 ± 2.5  0.0002 
ControlTransgenicP value
Colon length (cm)    8.5 ± 0.2    8.6 ± 0.1  NS 
Crypt height (μm)  102.6 ± 3.9  108.3 ± 2.3  NS 
Crypt height (No. cells)   20.1 ± 0.4   22.3 ± 0.2  0.0002 
Cell size (crypt height [μm]/    5.1 ± 0.1    4.9 ± 0.1  NS 
 crypt height [No. cells])       
Crypt circumference (No. cells)   16.3 ± 0.3   16.8 ± 0.2  NS 
Total No. cells per crypt  327.7 ± 7.2  372.8 ± 2.5  0.0002 

Results are shown as means ± SEM on a sample size of 10 mice/group. NS, not significantly different.  

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