Effect of PKC βII Transgene Expression on Proliferative Parameters in the Colon
| . | . | Control . | . | Transgenic . | . | P value . |
|---|---|---|---|---|---|---|
| Labeling index | ||||||
| Entire crypt | 21.4 ± 0.9 | 28.3 ± 0.2 | 0.0001 | |||
| Top 1/3 crypt | 0.2 ± 0.2 | 0 ± 0 | NS | |||
| Middle 1/3 crypt | 13.8 ± 2.5 | 17.8 ± 1.0 | NS | |||
| Bottom 1/3 crypt | 50.0 ± 2.7 | 67.5 ± 1.4 | 0.0005 | |||
| Proliferative zone | ||||||
| Entire crypt column | 37.1 ± 2.5 | 41.4 ± 1.1 | NS |
| . | . | Control . | . | Transgenic . | . | P value . |
|---|---|---|---|---|---|---|
| Labeling index | ||||||
| Entire crypt | 21.4 ± 0.9 | 28.3 ± 0.2 | 0.0001 | |||
| Top 1/3 crypt | 0.2 ± 0.2 | 0 ± 0 | NS | |||
| Middle 1/3 crypt | 13.8 ± 2.5 | 17.8 ± 1.0 | NS | |||
| Bottom 1/3 crypt | 50.0 ± 2.7 | 67.5 ± 1.4 | 0.0005 | |||
| Proliferative zone | ||||||
| Entire crypt column | 37.1 ± 2.5 | 41.4 ± 1.1 | NS |
Results are shown as means ± SEM on a sample size of four to five mice/group. NS, not significantly different, (P > 0.05).