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Table 1

Relative Protein Levels of Peripherin Compared with NF-L in Cytoskeletal Fractions of Dorsal and Ventral Roots

TissuesGenotypeRatio of peripherin to NF-L
Ventral root WT (n = 5) 0.090 ± 0.037 
 TPer (n = 3) 0.650 ± 0.092 
 Per (n = 4) 0.870 ± 0.130 
Dorsal root WT (n = 5) 0.316 ± 0.164 
 TPer (n = 3) 0.590 ± 0.095 
 Per (n = 4) 1.180 ± 0.057 
TissuesGenotypeRatio of peripherin to NF-L
Ventral root WT (n = 5) 0.090 ± 0.037 
 TPer (n = 3) 0.650 ± 0.092 
 Per (n = 4) 0.870 ± 0.130 
Dorsal root WT (n = 5) 0.316 ± 0.164 
 TPer (n = 3) 0.590 ± 0.095 
 Per (n = 4) 1.180 ± 0.057 

20 μm of Triton X-100–insoluble fractions were fractionated on SDS-PAGE and stained with Coomassie blue. The OD corresponding to the peripherin and NF-L bands were then evaluated by densitometry. Ratios were calculated by dividing the peripherin OD by the NF-L OD for each mice. Results are mean ± SD.

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