Outgrowth from Olfactory Bulb Explants
. | . | . | Percent of control . | ||||
---|---|---|---|---|---|---|---|
. | No. of experiments . | No. of explants . | Sum neurite length . | Average neurite length . | Neurite area . | Neurites per circumference . | No. of neurites . |
Control | 24 | 52 | 100 ± 14 | 100 ± 4 | 100 ± 10 | 100 ± 11 | 100 ± 11 |
rβ-netrin | |||||||
7 nM | 6 | 11 | 127 ± 31 | 109 ± 7 | 143 ± 23 | 108 ± 28 | 131 ± 25 |
14 nM | 20 | 41 | 246 ± 32 | 139 ± 11 | 160 ± 8 | 188 ± 18 | 189 ± 17 |
28 nM | 10 | 16 | 368 ± 39 | 154 ± 10 | 197 ± 25 | 265 ± 26 | 265 ± 17 |
14 nM + Ab | 6 | 12 | 108 ± 18 | 121 ± 15 | 112 ± 18 | 90 ± 15 | 100 ± 13 |
rβ-netrin ΔC | |||||||
19 nM | 4 | 8 | 587 ± 63 | 168 ± 11 | 235 ± 18 | 344 ± 68 | 370 ± 48 |
38 nM | 4 | 8 | 355 ± 91 | 135 ± 16 | 136 ± 26 | 285 ± 70 | 279 ± 46 |
190 nM | 5 | 15 | 65 ± 10 | 85 ± 18 | 64 ± 18 | 84 ± 9 | 78 ± 11 |
rγ2 | |||||||
15 nM | 10 | 20 | 217 ± 50 | 113 ± 9 | 136 ± 25 | 178 ± 23 | 185 ± 29 |
30 nM | 9 | 24 | 225 ± 60 | 130 ± 18 | 139 ± 26 | 151 ± 24 | 166 ± 27 |
60 nM | 3 | 8 | 82 ± 48 | 106 ± 15 | 65 ± 31 | 68 ± 27 | 91 ± 53 |
rγ3 | |||||||
9 nM | 10 | 23 | 215 ± 45 | 122 ± 14 | 146 ± 26 | 172 ± 28 | 177 ± 28 |
18 nM | 10 | 23 | 139 ± 27 | 102 ± 5 | 96 ± 13 | 117 ± 18 | 140 ± 24 |
36 nM | 2 | 7 | 47 ± 19 | 150 ± 65 | 49 ± 31 | 58 ± 0 | 42 ± 32 |
rβ2 | |||||||
8 nM | 3 | 8 | 65 ± 14 | 70 ± 6 | 51 ± 8 | 99 ± 22 | 89 ± 19 |
16 nM | 6 | 23 | 124 ± 12 | 103 ± 12 | 107 ± 26 | 132 ± 34 | 123 ± 31 |
32 nM | 3 | 10 | 188 ± 77 | 128 ± 16 | 192 ± 81 | 164 ± 58 | 166 ± 43 |
. | . | . | Percent of control . | ||||
---|---|---|---|---|---|---|---|
. | No. of experiments . | No. of explants . | Sum neurite length . | Average neurite length . | Neurite area . | Neurites per circumference . | No. of neurites . |
Control | 24 | 52 | 100 ± 14 | 100 ± 4 | 100 ± 10 | 100 ± 11 | 100 ± 11 |
rβ-netrin | |||||||
7 nM | 6 | 11 | 127 ± 31 | 109 ± 7 | 143 ± 23 | 108 ± 28 | 131 ± 25 |
14 nM | 20 | 41 | 246 ± 32 | 139 ± 11 | 160 ± 8 | 188 ± 18 | 189 ± 17 |
28 nM | 10 | 16 | 368 ± 39 | 154 ± 10 | 197 ± 25 | 265 ± 26 | 265 ± 17 |
14 nM + Ab | 6 | 12 | 108 ± 18 | 121 ± 15 | 112 ± 18 | 90 ± 15 | 100 ± 13 |
rβ-netrin ΔC | |||||||
19 nM | 4 | 8 | 587 ± 63 | 168 ± 11 | 235 ± 18 | 344 ± 68 | 370 ± 48 |
38 nM | 4 | 8 | 355 ± 91 | 135 ± 16 | 136 ± 26 | 285 ± 70 | 279 ± 46 |
190 nM | 5 | 15 | 65 ± 10 | 85 ± 18 | 64 ± 18 | 84 ± 9 | 78 ± 11 |
rγ2 | |||||||
15 nM | 10 | 20 | 217 ± 50 | 113 ± 9 | 136 ± 25 | 178 ± 23 | 185 ± 29 |
30 nM | 9 | 24 | 225 ± 60 | 130 ± 18 | 139 ± 26 | 151 ± 24 | 166 ± 27 |
60 nM | 3 | 8 | 82 ± 48 | 106 ± 15 | 65 ± 31 | 68 ± 27 | 91 ± 53 |
rγ3 | |||||||
9 nM | 10 | 23 | 215 ± 45 | 122 ± 14 | 146 ± 26 | 172 ± 28 | 177 ± 28 |
18 nM | 10 | 23 | 139 ± 27 | 102 ± 5 | 96 ± 13 | 117 ± 18 | 140 ± 24 |
36 nM | 2 | 7 | 47 ± 19 | 150 ± 65 | 49 ± 31 | 58 ± 0 | 42 ± 32 |
rβ2 | |||||||
8 nM | 3 | 8 | 65 ± 14 | 70 ± 6 | 51 ± 8 | 99 ± 22 | 89 ± 19 |
16 nM | 6 | 23 | 124 ± 12 | 103 ± 12 | 107 ± 26 | 132 ± 34 | 123 ± 31 |
32 nM | 3 | 10 | 188 ± 77 | 128 ± 16 | 192 ± 81 | 164 ± 58 | 166 ± 43 |