Quantitative comparison of neurite development in cultured hippocampal neurons
Neurite length after 3 d in culture . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|
| Genotype map2map1b | Axon | Minor process | ||||||
| Mean ± SD | n | Mean ± SD | n | |||||
| μm | μm | |||||||
| +/− +/+ | 186.4 ± 54.4a | 90 | 43.5 ± 18.4a | 424 | ||||
| −/− +/+ | 153.2 ± 49.8a | 90 | 41.0 ± 17.5a | 391 | ||||
| +/− −/− | 107.6 ± 41.3 | 90 | 32.6 ± 12.7a | 389 | ||||
| −/− −/− | 101.0 ± 41.8 | 90 | 27.7 ± 11.3 | 380 | ||||
Neurite length after 3 d in culture . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|
| Genotype map2map1b | Axon | Minor process | ||||||
| Mean ± SD | n | Mean ± SD | n | |||||
| μm | μm | |||||||
| +/− +/+ | 186.4 ± 54.4a | 90 | 43.5 ± 18.4a | 424 | ||||
| −/− +/+ | 153.2 ± 49.8a | 90 | 41.0 ± 17.5a | 391 | ||||
| +/− −/− | 107.6 ± 41.3 | 90 | 32.6 ± 12.7a | 389 | ||||
| −/− −/− | 101.0 ± 41.8 | 90 | 27.7 ± 11.3 | 380 | ||||
Significantly different from map2−/−map1b−/− mice at P < 0.01 using the post hoc test. Values based on three independent experiments. n, number of neurites examined.