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Table I.

Quantitative comparison of neurite development in cultured hippocampal neurons


Neurite length after 3 d in culture
Genotype map2map1b Axon  Minor process  
 Mean ± SD Mean ± SD 

 
μm
 

 
μm
 

 
+/− +/+ 186.4 ± 54.4a 90 43.5 ± 18.4a 424 
−/− +/+ 153.2 ± 49.8a 90 41.0 ± 17.5a 391 
+/− −/− 107.6 ± 41.3 90 32.6 ± 12.7a 389 
−/− −/−
 
101.0 ± 41.8
 
90
 
27.7 ± 11.3
 
380
 

Neurite length after 3 d in culture
Genotype map2map1b Axon  Minor process  
 Mean ± SD Mean ± SD 

 
μm
 

 
μm
 

 
+/− +/+ 186.4 ± 54.4a 90 43.5 ± 18.4a 424 
−/− +/+ 153.2 ± 49.8a 90 41.0 ± 17.5a 391 
+/− −/− 107.6 ± 41.3 90 32.6 ± 12.7a 389 
−/− −/−
 
101.0 ± 41.8
 
90
 
27.7 ± 11.3
 
380
 
a

Significantly different from map2−/−map1b−/− mice at P < 0.01 using the post hoc test. Values based on three independent experiments. n, number of neurites examined.

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