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Table I.

Number of facial and spinal motor neurons in the brain stem and lumbar (L1–L6) spinal cord, respectively, of 3.5-mo-old SMN2;Smn/ type III SMA mice heterozygous for the A2G transgene and age-matched controls


Type of motor neurons

Type III SMA

Normal

Reduction
Facial nucleus 2,994 ± 94 (n = 4) 3,695 ± 171 (n = 2) −19% (P < 0.05) 
Spinal motor neurons
 
3,144 ± 201 (n = 4)
 
4,421 ± 76 (n = 2)
 
−29% (P < 0.05)
 

Type of motor neurons

Type III SMA

Normal

Reduction
Facial nucleus 2,994 ± 94 (n = 4) 3,695 ± 171 (n = 2) −19% (P < 0.05) 
Spinal motor neurons
 
3,144 ± 201 (n = 4)
 
4,421 ± 76 (n = 2)
 
−29% (P < 0.05)
 
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