Rockefeller University Press

Table I.

Summary of changes of integrin gene expression in mAChR KO versus WT mice

	M₃^−/−					M₄^−/−
	In vivo (IF)			In vitro (WB)	In vivo (IF)			In vitro (WB)
Integrin	N	W		N	W
α₂	↓^{^a}	↓^{^a}	↓	↑^{^a}	↑	↑^{^a}
α₃	↓^{^a}	↓^{^a}	↓^{^a}	↑^{^a}	↑	↑
α₅	↑^{^a}	↑^{^a}	↑	↓^{^a}	↑^{^a}	↓^{^a}
α_V	↑^{^a}	↑^{^a}	↑^{^a}	↓^{^a}	↑^{^a}	↓^{^a}
β₅	↑^{^a}	↑^{^a}	↑^{^a}	↓^{^a}	↓^{^a}	↓

	M₃^−/−					M₄^−/−
	In vivo (IF)			In vitro (WB)	In vivo (IF)			In vitro (WB)
Integrin	N	W		N	W
α₂	↓^{^a}	↓^{^a}	↓	↑^{^a}	↑	↑^{^a}
α₃	↓^{^a}	↓^{^a}	↓^{^a}	↑^{^a}	↑	↑
α₅	↑^{^a}	↑^{^a}	↑	↓^{^a}	↑^{^a}	↓^{^a}
α_V	↑^{^a}	↑^{^a}	↑^{^a}	↓^{^a}	↑^{^a}	↓^{^a}
β₅	↑^{^a}	↑^{^a}	↑^{^a}	↓^{^a}	↓^{^a}	↓

^a

P < 0.05 and the rest are P > 0.05 compared to WT mice.

IF, immunofluorescence; N, normal (intact) skin; W, wound tissue; WB, Western blot.