Analysis of the targeting of NF constructs to the AIS
| Domain . | NF
n = 206 . | ICAM1
n = 84 . | ICAM1/NF-CD
n = 96 . | NF-ED/ICAM1
n = 82 . | NFΔABD
n = 57 . | NFΔIg
n = 49 . | NFΔFNIII
n = 177 . | NFΔmucin
n = 245 . |
|---|---|---|---|---|---|---|---|---|
| AIS | 73 | 0 | 88 | 0 | 0 | 63 | 76 | 90 |
| AIS+ | 27 | 0 | 11 | 0 | 0 | 37 | 24 | 10 |
| S + D | 0 | 70 | 0 | 44 | 9 | 0 | 0 | 0 |
| S + D + A | 0 | 30 | 1 | 41 | 65 | 0 | 0 | 0 |
| S | 0 | 0 | 0 | 15 | 21 | 0 | 0 | 0 |
| Domain . | NF
n = 206 . | ICAM1
n = 84 . | ICAM1/NF-CD
n = 96 . | NF-ED/ICAM1
n = 82 . | NFΔABD
n = 57 . | NFΔIg
n = 49 . | NFΔFNIII
n = 177 . | NFΔmucin
n = 245 . |
|---|---|---|---|---|---|---|---|---|
| AIS | 73 | 0 | 88 | 0 | 0 | 63 | 76 | 90 |
| AIS+ | 27 | 0 | 11 | 0 | 0 | 37 | 24 | 10 |
| S + D | 0 | 70 | 0 | 44 | 9 | 0 | 0 | 0 |
| S + D + A | 0 | 30 | 1 | 41 | 65 | 0 | 0 | 0 |
| S | 0 | 0 | 0 | 15 | 21 | 0 | 0 | 0 |
The percentages of Hc neurons exhibiting AIS, somatic (S), dendritic (D), and axonal (A) staining are shown. AIS+ indicates enriched staining at the AIS with minor membrane labeling present elsewhere on the neuron.