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Table II.

Quantification of aberrant cells during cytokinesis and interphase after 48-h PRP4 RNAi in HeLa cells

RNAi treatmentCytokinesis
Interphase cells

With micronuclei
With DNA bridge
With micronuclei
 % % % 
Control RNAi 6.2 ± 1.2 3.0 ± 2.9 3.9 ± 0.8 
PRP4 RNAi 44.2 ± 13.9 21.0 ± 5.56 30.9 ± 6.4 
RNAi treatmentCytokinesis
Interphase cells

With micronuclei
With DNA bridge
With micronuclei
 % % % 
Control RNAi 6.2 ± 1.2 3.0 ± 2.9 3.9 ± 0.8 
PRP4 RNAi 44.2 ± 13.9 21.0 ± 5.56 30.9 ± 6.4 

Quantification of aberrant cells in cytokinesis and interphase after PRP4 RNAi. The values indicate the percentage of cytokinesis or interphase cells displaying residual DNA bridges and/or micronuclei after PRP4 RNAi treatment.

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