Skip to Main Content
Table I.

Sepharose bead proteome: most common protein classes

Protein class
Most commonly found
Cytoskeletal/structural/
     motility proteins Actin 
 Cofilin 
 Desmin 
 Desmoplakin 
 Epiplakin 
 Filamin 
 Myosin 
 Peripherin 
 Plectin 
 Tropomyosin 
 Tubulin 
 Vimentin 
DEAD box proteins  
Eukaryotic translation elongation
     and initiation factors  
Heat shock proteins  
Histones  
hnRNP proteins  
Ribosomal proteins  
Protein class
Most commonly found
Cytoskeletal/structural/
     motility proteins Actin 
 Cofilin 
 Desmin 
 Desmoplakin 
 Epiplakin 
 Filamin 
 Myosin 
 Peripherin 
 Plectin 
 Tropomyosin 
 Tubulin 
 Vimentin 
DEAD box proteins  
Eukaryotic translation elongation
     and initiation factors  
Heat shock proteins  
Histones  
hnRNP proteins  
Ribosomal proteins  

Proteins that bind nonspecifically to Sepharose fall into several distinct classes, as shown here, and are found in nearly every SILAC immunoprecipitation experiment carried out using Sepharose as an affinity matrix.

Close Modal

or Create an Account

Close Modal
Close Modal