Rockefeller University Press

Table I.

Genotype incidence and frequencies of pups and embryos from NuMA^Neo/+, NuMA^flox/+, and NuMA^Δ22/+ heterozygous crosses

Parental genotypes	Progeny	Progeny genotypes
		+	Neo	Neo	flox	flox	Δ22	Δ22
		+	+	Neo	+	flox	+	Δ22
Neo/+ × Neo/+	Pups^a	23 (26%)	65 (74%)	0	NA	NA	NA	NA
	Embryos^b	21 (42%)	29 (58%)	0	NA	NA	NA	NA
flox/+ × flox/+	Pups	34 (31%)	NA	NA	53 (47%)	25 (22%)	NA	NA
Δ22/+ × Δ22/+	Pups	14 (33%)	NA	NA	NA	NA	28 (67%)	0
	Embryos	7 (32%)	NA	NA	NA	NA	15 (68%)	0

Parental genotypes	Progeny	Progeny genotypes
		+	Neo	Neo	flox	flox	Δ22	Δ22
		+	+	Neo	+	flox	+	Δ22
Neo/+ × Neo/+	Pups^a	23 (26%)	65 (74%)	0	NA	NA	NA	NA
	Embryos^b	21 (42%)	29 (58%)	0	NA	NA	NA	NA
flox/+ × flox/+	Pups	34 (31%)	NA	NA	53 (47%)	25 (22%)	NA	NA
Δ22/+ × Δ22/+	Pups	14 (33%)	NA	NA	NA	NA	28 (67%)	0
	Embryos	7 (32%)	NA	NA	NA	NA	15 (68%)	0

Neo, NuMA^Neo; flox, NuMA^flox; Δ22, NuMA^Δ22; +, wild-type NuMA allele; NA, not applicable.

Mouse pups were genotyped at postnatal day 21.

Embryos were collected between embryonic days 9.5 and 14.5.