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Table 1.
Clinical characterization of Sig K1-high/low DLBCL samples
Sig K1-highSig K1-lowP valuea
No. of patients 28 28  
Age, yr   0.2847 
>60 (%) 16 (57.1) 11 (39.3)  
≤60 (%) 12 (42.9) 17 (60.7)  
Gender   0.1707 
Male (%) 14 (50.0) 20 (71.4)  
Female (%) 14 (50.0) 8 (28.6)  
Subtypeb   0.0148 
ABC (%) 16 (72.7) 7 (33.3)  
GCB (%) 6 (27.3) 14 (66.7)  
Stage   1.0000 
I–II (%) 12 (42.9) 13 (46.4)  
III–IV (%) 16 (57.1) 15 (53.6)  
Primary or relapse   0.3516 
Primary (%) 24 (85.7) 27 (96.4)  
Relapse (%) 4 (14.3) 1 (3.6)  
HBsAg status   0.7585 
Positive (%) 6 (21.4) 8 (28.6)  
Negative (%) 22 (78.6) 20 (71.4)  
MSIseq   0.5279 
MSI (%) 5 (17.9) 8 (28.6)  
MSS (%) 23 (82.1) 20 (71.4)  
Treatmentb   0.2238 
CHOP (%) 5 (18.5) 9 (32.1)  
RCHOP (%) 22 (81.5) 17 (60.7)  
Sig K1-highSig K1-lowP valuea
No. of patients 28 28  
Age, yr   0.2847 
>60 (%) 16 (57.1) 11 (39.3)  
≤60 (%) 12 (42.9) 17 (60.7)  
Gender   0.1707 
Male (%) 14 (50.0) 20 (71.4)  
Female (%) 14 (50.0) 8 (28.6)  
Subtypeb   0.0148 
ABC (%) 16 (72.7) 7 (33.3)  
GCB (%) 6 (27.3) 14 (66.7)  
Stage   1.0000 
I–II (%) 12 (42.9) 13 (46.4)  
III–IV (%) 16 (57.1) 15 (53.6)  
Primary or relapse   0.3516 
Primary (%) 24 (85.7) 27 (96.4)  
Relapse (%) 4 (14.3) 1 (3.6)  
HBsAg status   0.7585 
Positive (%) 6 (21.4) 8 (28.6)  
Negative (%) 22 (78.6) 20 (71.4)  
MSIseq   0.5279 
MSI (%) 5 (17.9) 8 (28.6)  
MSS (%) 23 (82.1) 20 (71.4)  
Treatmentb   0.2238 
CHOP (%) 5 (18.5) 9 (32.1)  
RCHOP (%) 22 (81.5) 17 (60.7)  

Values are reported as n (%) of patients unless indicated otherwise. CHOP, a chemotherapy combination of cyclophosphamide, doxorubicin hydrochloride, vincristine (Oncovin, Vincasar PFS), and prednisolone; HBsAg, hepatitis B virus surface antigen; RCHOP, a chemotherapy combination of rituximab (Rituxan) and CHOP; Sig, signature.

a

Fisher's exact test was used for comparison. Significant value (P < 0.05) is highlighted in bold.

b

The calculation was based on 43 or 53 samples with available data.

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