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Table 1.
SARS-CoV-2 spike protein variants tested
B.1 lineage (D614G)B.1 + D80YB.1 + S98FB.1 + A222VB.1 + N439KB.1 + S477NB.1 + E484KB.1 + Y453F, ΔH69, ΔV70Mink Cluster 5B.1.1.7 UK (501Y.V1)B.1.351 + R246I RSA (501Y.V2)B.1.351 + D215G RSA (501Y.V2)B.1.351 + D215G + Δ242-244 RSA (501Y.V2)
S1 NTD        Δ69–70 Δ69–70 Δ69–70    
1–685 13–305  D80Y         D80A D80A D80A 
   S98F           
          Δ144    
            D215G D215G 
    A222V          
           L242H L242H Δ242–244 
           R246I   
RBD           K417N K417N K417N 
330–521     N439K         
        Y453F Y453F     
      S477N        
       E484K    E484K E484K E484K 
          N501Y N501Y N501Y N501Y 
 D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G 
          A570D    
          P681H    
S2          I692V     
686–1273            A701V A701V A701V 
          T716I    
          S982A    
          D1118H    
         M1229I     
B.1 lineage (D614G)B.1 + D80YB.1 + S98FB.1 + A222VB.1 + N439KB.1 + S477NB.1 + E484KB.1 + Y453F, ΔH69, ΔV70Mink Cluster 5B.1.1.7 UK (501Y.V1)B.1.351 + R246I RSA (501Y.V2)B.1.351 + D215G RSA (501Y.V2)B.1.351 + D215G + Δ242-244 RSA (501Y.V2)
S1 NTD        Δ69–70 Δ69–70 Δ69–70    
1–685 13–305  D80Y         D80A D80A D80A 
   S98F           
          Δ144    
            D215G D215G 
    A222V          
           L242H L242H Δ242–244 
           R246I   
RBD           K417N K417N K417N 
330–521     N439K         
        Y453F Y453F     
      S477N        
       E484K    E484K E484K E484K 
          N501Y N501Y N501Y N501Y 
 D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G D614G 
          A570D    
          P681H    
S2          I692V     
686–1273            A701V A701V A701V 
          T716I    
          S982A    
          D1118H    
         M1229I     

Gray shading indicates the RBD region.

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